Thorne Vitamin D Liquid 500 IU per Drop

Bone & Dental Health: Vitamin D3 activates osteocalcin, the calcium-binding protein essential for mineralizing bone matrix and maintaining skeletal integrity throughout the lifespan. By enhancing intestinal calcium and phosphorus absorption, this formula helps preserve bone mineral density while supporting healthy tooth enamel formation. The D3 form (cholecalciferol) demonstrates superior bioavailability compared to D2, ensuring efficient conversion to the active hormone calcitriol that regulates calcium homeostasis.

Immune System Modulation: Cholecalciferol supports innate immune function by stimulating antimicrobial peptide production in white blood cells and modulating T-cell responses for balanced immune surveillance. Adequate vitamin D levels help maintain the body's first-line defence mechanisms while supporting appropriate inflammatory responses. This is particularly valuable during Canadian winters when reduced sun exposure can compromise immune resilience and increase susceptibility to seasonal challenges.

Cardiovascular & Muscle Support: Vitamin D receptors in cardiac muscle and vascular endothelium enable this nutrient to support healthy blood pressure regulation and vascular elasticity through effects on the renin-angiotensin system. It also maintains muscle protein synthesis and neuromuscular function, helping preserve lean muscle mass and strength—critical for preventing falls in older adults and supporting athletic performance in active individuals.

Mood & Cognitive Function: Vitamin D influences neurotransmitter synthesis and neuroplasticity, with receptors present throughout the brain's limbic system responsible for emotional regulation. By supporting serotonin pathways and protecting against oxidative stress in neural tissue, adequate vitamin D status correlates with positive mood and cognitive clarity. The liquid format ensures consistent daily intake to maintain stable serum 25-hydroxyvitamin D levels year-round.