CanPrev B9 Folate 200mcg Drops - Active Methylfolate

Red Blood Cell Formation & Anemia Prevention: L-5-methyltetrahydrofolate works synergistically with vitamin B12 and vitamin C to drive erythropoiesis—the production of red blood cells in bone marrow. By providing folate in its active form, these drops support hemoglobin synthesis and prevent megaloblastic anemia, a condition where folate deficiency causes the body to produce abnormally large, immature red blood cells that cannot effectively transport oxygen to tissues, leading to persistent fatigue and weakness.

Neural Tube Defect Risk Reduction: For women of childbearing age, adequate folate intake is critical during the periconceptional period. This supplement provides the bioavailable form of folate necessary for proper DNA synthesis and cell division during fetal neural tube development. When taken daily at 400mcg (4 drops for adults) beginning at least three months before conception and continuing through early pregnancy, active folate significantly reduces the risk of neural tube defects such as spina bifida and anencephaly.

Cellular Metabolism & Energy Production: As a crucial cofactor in one-carbon metabolism, methylfolate facilitates the conversion of homocysteine to methionine, supporting methylation reactions throughout the body. These biochemical processes are essential for DNA repair, gene expression, neurotransmitter synthesis, and cellular energy production. By maintaining healthy homocysteine levels and supporting efficient methylation, these drops help combat the cellular fatigue that underlies many cases of persistent tiredness.

Superior Bioavailability for MTHFR Variants: Unlike synthetic folic acid, which requires conversion through the MTHFR enzyme pathway, L-5-methyltetrahydrofolate is the ready-to-use form of folate. This is particularly beneficial for individuals with MTHFR gene polymorphisms (affecting up to 40% of the population) who have reduced ability to convert folic acid to its active form. The liquid drop delivery system with methylcobalamin B12 ensures optimal absorption and immediate cellular utilization regardless of genetic variations.